Note that Windows Defender is an anti-spyware solution only. It is not an anti-malware solution.
MSE is a full anti-malware solution (anti-virus, anti-spyware, anti-Trojan, etc.) and automatically disables Windows Defender upon installation.
You do not need, and should not run Spyware Doctor and MSE at the same time. While conflicts are not the problem they used to be, it is still two dogs guarding the same bone - at best, running both at the same time unnecessarily ties up extra resources (RAM and CPU utilization). I recommend disabling (or uninstalling Spyware Doctor) and sticking with MSE as your main AM solution. Then use MBAM (or SD if you keep it) for "on-demand" supplemental scanning.