The M500 has a slight advantage on Sequential write. But only if
you're buying the 480GB or 960GB ones.
http://www.anandtech.com/show/6884/crucial-micron-m500-review-960gb-480gb-240gb-120gb
The table on that page, claims write endurance of the individual chips
is 3000 writes on the 25nm (M4) and 3000 writes on the 20mm (M500
128Gbit chip).
So the write endurance hasn't changed. It's possible though, that the
change
in page size, might have an effect on write amplification. The page is
bigger than the 4KB cluster used in NTFS.
*******
Some day, we won't have to worry about write endurance. I read a blurb the
other day, where a researcher has figure out that "annealing" flash cells,
repairs the damage done by writes. But it will be some time, before the
idea of having internal heaters, will appear in practical devices, if at
all.
Still, it's an intriguing idea.
Maybe ten years from now, we really will be able to treat flash drives,
like they were regular hard drives (no special treatment, defragment them
if you want, etc).
*******
As with any brand new product, wait three months for the eager buyers
to test them for you. If there are no overwhelmingly negative reviews,
buy one for a test drive.
Paul