I have never used this particular driver updater but I tend to be leery of all driver update programs based on past experience; even windows updates "recommended" driver updates are sometimes wrong. Manufacturers update drivers all the time and a program like this is only as accurate as its' last driver database update.
If the wrong driver is installed, your system may not boot properly. For that reason the best method of updating your drivers is to visit the manufacturer's websites of your various components (motherboard, video card, Network Interface Card (NIC), Printer, etc) and get the proper drivers directly from them.
That being said, if you do use a driver update program then use it as safely as possible:
1. create a restore point
2. install one and only one driver
3. reboot the computer and make sure everything still works; if there is a problem then reboot into safe mode and restore from that last restore point and don't install that "problem" driver again
4. repeat steps 1 through 3 for each different driver.